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Saracens boss Mark McCall has made six changes for the sold-out match. Alex Lewington returns to the wing, meaning a switch to full-back for Elliot Daly, while Alex Lozowski comes into the centre alongside captain Brad Barritt.
Scrum-half Richard Wigglesworth resumes his half-back partnership with Owen Farrell and with Scotland international Sean Maitland ruled out late due to injury, he is replaced on the wing by academy graduate Rotimi Segun.
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Warriors number eight GJ van Velze will make his first Premiership start of the season after featuring as a replacement in all seven matches. He replaces Cornell du Preez who suffered an ankle injury in last weekend’s win over London Irish.
Van Velze is one of six changes, with tighthead prop Nick Schonert (gashed head) and fly-half Duncan Weir (jaw) also ruled out by injuries sustained against Irish. Richard Palframan starts in place of Schonert with Jono Lance called up to replace Weir.
Michael Heaney starts at scrum-half with Jamie Shillcock, a try-scorer against Harlequins in November on his last Premiership start, is recalled at full-back.
Samoa international wing Ed Fidow will make his second Premiership appearance having recovered from the concussion suffered after he had scored a hat-trick of tries against Wasps A in a recent Premiership Rugby Shield match.
SARACENS: 15. Elliot Daly; 14. Rotimi Segun, 13. Alex Lozowski, 12. Brad Barritt (capt), 11. Alex Lewington; 10. Owen Farrell, 9. Richard Wigglesworth; 1. Mako Vunipola, 2. Jamie George, 3. Titi Lamositele, 4. Maro Itoje, 5. Will Skelton, 6. Nick Isiekwe, 7. Ben Earl, 8. Billy Vunipola. Reps: 16. Jack Singleton, 17. Richard Barrington, 18. Vincent Koch, 19. Joel Kpoku, 20. Jackson Wray, 21. Ben Spencer, 22. Manu Vunipola, 23. Duncan Taylor.
WORCESTER WARRIORS: 15. Jamie Shillcock; 14. Ed Fidow, 13. Ashley Beck, 12. Ryan Mills, 11. Tom Howe; 10. Jono Lance, 9. Michael Heaney; 1. Callum Black, 2. Matt Moulds (capt), 3. Richard Palframan, 4. Anton Bresler, 5. Graham Kitchener, 6. Ted Hill, 7. Sam Lewis, 8. GJ van Velze. Reps: 16. Joe Taufete’e, 17. Ryan Bower, 18. Conor Carey, 19. Michael Fatialofa, 20. Marco Mama, 21. Francois Hougaard, 22. Scott van Breda, 23. Ollie Lawrence.
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