Marx missed the June clashes with Wales and England with a hamstring problem, while Whiteley has been out of Springboks action for more than a year due to a groin injury and Louw is also yet to feature in 2018.
“Our forward depth is very good indeed and the competition for places in the team is healthy, which can only be a good thing for us as we continue to build the depth of our squad,” said Springboks head coach Rassie Erasmus.
Four big guys return to the Bok pack this weekend to face @lospumas – they are @EbenEtzebeth @M_marxi2 @FloLouw @WarrenWhiteley. Andre Esterhuizen and @Makazole16 will be starting in the backline. Check out the team for Saturday here. @CastleLagerSA @MTNza @SanzarTRC #LoveRugby pic.twitter.com/UdeSBXnwDm
— South African Rugby (@Springboks) August 16, 2018
Figallo – the only non-Jaguares player in the side – has not featured for the Pumas since they lost the third-place play-off at the 2015 Rugby World Cup.
South Africa: Willie le Roux, Makazole Mapimpi, Lukhanyo Am, Andre Esterhuizen, Aphiwe Dyantyi, Handre Pollard, Faf de Klerk; Tendai Mtawarira, Malcolm Marx, Frans Malherbe, Eben Etzebeth, Pieter-Steph du Toit, Francois Louw, Siya Kolisi, Warren Whiteley.
Argentina: Emiliano Boffelli, Bautista Delguy, Matias Moroni, Bautista Ezcurra, Ramiro Moyano, Nicolas Sanchez, Gonzalo Bertranou; Nahuel Tetaz Chaparro, Agustin Creevy, Juan Figallo, Guido Petti, Matias Alemanno, Pablo Matera, Marcos Kremer, Javier Ortega Desio.