Toulon belied their lowly league position by tearing Lyon apart, Filipo Nakosi crossing for a hat-trick of tries to help the hosts run out comfortable 40-7 winners.
Liam Messam, Josua Tuisova and Daniel Ikpefan also touched down for Toulon, who had lost seven of their previous 11 league outings but scored 28 unanswered points before the break at Stade Mayol.
Lyon put up more of a fight in the second half but have now lost three on the spin in all competitions following back-to-back defeats against Glasgow Warriors in the European Champions Cup.
The try of the game however belonged to Messam. The former All Black followed up a Francois Trinh-Duc penalty in the second minute of the game. The ball bounced off the crossbar and into his hands and the former All Black backrow, who scored.
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