Wallabies coach Michael Cheika has made four changes to his starting fifteen ahead of Australia’s Test against South Africa in Port Elizabeth on Saturday.
Tupou will bookend the scrum alongside Scott Sio who is set to notch his 50th Test cap.
In the other change, Adam Coleman re-gains his spot at lock after coming off the bench against Argentina on the Gold Coast.
Australia haven’t tasted victory in South Africa since 2011 but did earn a draw in the Republic last year, when both sides fought out a 27-all stalemate in Bloemfontein.
Saturday’s clash will be the first meeting between the two sides in Port Elizabeth since 1963, when South Africa won 22-6 to level the four-match Test series.
1. Scott Sio (49 Tests)
2. Tatafu Polota-Nau (86 Tests)
3. Taniela Tupou (6 Tests)
4. Adam Coleman (26 Tests)
5. Izack Rodda (11 Tests)
6. Ned Hanigan (15 Tests)
7. Michael Hooper (c) (85 Tests)
8. David Pocock (73 Tests)
9. Will Genia (94 Tests)
10. Kurtley Beale (78 Tests)
11. Marika Koroibete (15 Tests)
12. Matt Toomua (37 Tests)
13. Reece Hodge (31 Tests)
14. Israel Folau (67 Tests)
15. Dane Haylett-Petty (25 Tests)
16. Folau Faingaa (3 Tests)
17. Sekope Kepu (97 Tests)
18. Allan Alaalatoa (27 Tests)
19. Rory Arnold (17 Tests)
20. Rob Simmons (88 Tests)
21. Nick Phipps (67 Tests)
22. Bernard Foley (62 Tests)
23. Jack Maddocks (4 Tests)
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