England lock Ollie Chessum will return to Leicester Tigers' starting XV on Sunday as his side host Saracens in the Gallagher Premiership.
England captain Maro Itoje will return to captain a Saracens side containing four of his international team-mates during the Guinness Six Nations when they host Harlequins in the Gallagher Premiership on Saturday.
England fly-half Fin Smith has returned to Northampton Saints' starting line-up a week after the Guinness Six Nations campaign came to a close as his side host Leicester Tigers on Friday in the East Midlands Derby in the Gallagher Premiership.
If Andy Farrell opts to take only one specialist left wing to Australia, Sunday's 'contest within a contest' may prove pivotal.
The double Guinness Six Nations champions began their quest for an historic hat-trick of titles with a 27-22 win over England last Saturday that was far more comfortable than the scoreline suggested.
Ireland player ratings: Simon Easterby's Ireland were the second-best side in the first forty, but a strong final 30 minutes for the home side eventually saw them find their way to a 27-22 win.
Tadhg Beirne moves into the second row and Ryan Baird gets a rare international start.
Ireland head coach Andy Farrell has named his 36-player squad that will prepare to take on Wales on Saturday, with uncapped Munster duo Oli Jager and Tom Ahern receiving call-ups.
British and Irish Lion Iain Henderson has been recalled to the Ireland set-up after a positive Covid-19 test last week.
Sean O'Brien has proved his fitness for Ireland's trip to Scotland, while Iain Henderson comes in alongside Devin Toner.