The 27-year-old prop, capped 51 times by England, suffered a calf strain in his club’s European Champions Cup loss to Glasgow Warriors on Sunday and Sarries confirmed he will be sidelined for “around six weeks”.
Lock Nick Isiekwe, another who England coach Eddie Jones may have called on next month, is also out for eight weeks.
Billy Vunipola, Mako’s brother, is out due to a fractured arm suffered in the same game his younger sibling sustained his problem.
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