Genge, the Leicester prop, was forced to withdraw from a session at the squad’s London camp on Thursday because of an ankle injury but has since made a rapid recovery.
“Ellis went fully at it today (Friday) – live set piece, live scrums. He trained and did the whole session,” assistant coach Neal Hatley said.
“He’s responded unbelievably well to treatment last night and charged through training today.”
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Watch: England team train during Six Nations week off.
Vunipola was a marauding presence in the first two rounds of the Championship and his injury has robbed England of their most effective forward.
Into the void created in the number one jersey must step either Genge or Ben Moon, both of whom are Test rookies but have also acquitted themselves well in the international future.
“We saw over the autumn that Moon is a glue player. He does the basics very, very well and he allows the rest of the team to operate around him,” Hatley said.
“Ellis is also very aggressive. He’s an aggressive scrummager. He has a good ball carrying threat and is explosive. He moves off the line quickly.
“What Mako does for this team can’t be understated, but we’re excited about getting a good 80 minutes at loosehead prop against Wales.”
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