Taylor came off the bench as a replacement at the Stade de France after Coles suffered a ruptured ACL in last weekend’s 38-18 win over France in Paris.
Coach Steve Hansen said: “Scotland will be a formidable opponent who, from all indications, will be looking to play skillful rugby and an up-tempo game.
“Therefore, we’ll need to meet this challenge head-on and be prepared to empty the tank and exert our own pressure upon them through both our physicality, our own tempo in the game and executing our skills at the highest level.”
Du Preez will make his first Scotland start, while the uncapped Luke Hamilton steps up to the bench.
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